منابع مشابه
Primary Sjogrens Syndrome in a Child
Sjögren syndrome is uncommon in children and occurs most often in association with autoimmune diseases (secondary Sjögren syndrome). We describe the clinical and biological features of a 7-year-old girl with primary Sjögren syndrome revealed by recurrent parotiditis. CASE REPORT A 7-year-old girl was referred for investigation of multiple episodes of parotid swelling since age 4 years, withou...
متن کامل3431 Conjunctiva immunopathology in primary sjogrens syndrome (1° S.S.)
Aim: To evaluate the histological changes and immune response of conjuctiva in patients (pts) with lo S.S. Materials and Methods: We studied conjunctiial biopsies from 15 pts with I0 S.S. and 2 normal controls using 1) paraflfn section screening for the quality of conjunctival epithelium (CE), the number of goblet cells (GC) and the degree of inflammation, 2) Mo-abs and Pabs to: Tlymphocytes, T...
متن کاملFatigue in primary Sjögren's syndrome.
OBJECTIVE To assess fatigue in relation to depression, blood pressure, and plasma catecholamines in patients with primary Sjögren's syndrome (SS), in comparison with healthy controls and patients with rheumatoid arthritis. METHODS For the assessment of fatigue the Multidimensional Fatigue Inventory (MFI) was used, a 20 item questionnaire, covering the following dimensions: general fatigue, ph...
متن کاملProfiling Micro-RNA expression in patients with Primary Sjogrens Syndrome – contribution to disease pathogenesis
Background Sjogrens syndrome (SS) is a chronic autoimmune disorder, characterised by lymphocytic infiltration resulting in exocrine gland destruction and other extra-glandular manifestations [1]. Currently there is no definitive diagnostic test, and the immuno-pathology is not fully understood. Recently focus has shifted to investigating microRNAs (miRs) in an effort to understand the mechanism...
متن کاملHeat shock proteins and chronic fatigue in primary Sjögren’s syndrome
Fatigue occurs frequently in patients with cancer, neurological diseases and chronic inflammatory diseases, but the biological mechanisms that lead to and regulate fatigue are largely unknown. When the innate immune system is activated, heat shock proteins (HSPs) are produced to protect cells. Some extracellular HSPs appear to recognize cellular targets in the brain, and we hypothesize that fat...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1998
ISSN: 0003-4967
DOI: 10.1136/ard.57.5.291